👉 The Pf Fluid, developed by Pfizer, is a groundbreaking lipid nanoparticle (LNP) delivery system designed to transport therapeutic molecules, such as mRNA, into cells efficiently. These LNPs are composed of a core of ionizable lipids, helper lipids, cholesterol, and polyethylene glycol (PEG)-modified lipids, which collectively form a stable, biocompatible structure. The ionizable lipids facilitate the encapsulation and release of the therapeutic payload within endosomes, while the helper lipids and PEGylation enhance stability, reduce immunogenicity, and improve circulation time in the bloodstream. This sophisticated design enables the Pf Fluid to effectively deliver mRNA vaccines and other therapeutic agents, driving advancements in personalized medicine and vaccine development.
